gene 2,462 words KG: SLC30A5
Contents

SLC30A5 — Solute Carrier Family 3 Member 0A5 (SLC30A5)

🧬 Gene Info
Gene SymbolSLC30A5
Full NameSolute Carrier Family 3 Member 0A5 (SLC30A5)
Chromosome3p21.1
Protein TypeTransporter
Functionis a member of the SLC30 family of zinc transporters that facilitates zinc efflux from the cytoplasm into intracellular compartments[@huang2013].
Primary Expressionvarious tissues including the brain, making it relevant to neurodegenerative disease research[@jackson2007]
Subcellular Localizationthe Golgi apparatus and plasma membrane, where it plays a critical role in zinc sequestration and homeostasis[@nishida20
Amino Acids638 aa
Exons13
UniProt IDQ8TAP9
NCBI Gene ID7783
Ensembl IDENSG00000146039
OMIM607339
GeneCardsSLC30A5
Human Protein AtlasSLC30A5
Associated Diseasesneurodegeneration
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (4)

SASP-Mediated Complement Cascade Amplification
Score: 0.87
Matrix Stiffness Normalization via Targeted Lysyl Oxidase In
Score: 0.71
Complement C1QA Spatial Gradient in Cortical Layers
Score: 0.68
Pharmacological Enhancement of APOE4 Glycosylation
Score: 0.62

Related Analyses (2)

Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (11)

Viral and Post-Infectious Mechanisms in ALS — Experiment Des
clinical · proposed · Score: 0.40
Proposed experiment from debate on Senolytics targeting p16/
falsification · proposed · Score: 0.40
Mechanism: Why Does Amyloid Removal Only Slow Decline 27%?
clinical · proposed · Score: 0.40
Experiment: Autoimmune Hypothesis Testing in AD
clinical · proposed · Score: 0.40
Mixed Pathology Effects on Parkinson's Disease Progression a
clinical · proposed · Score: 0.40

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in

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