| Gene Symbol | SLC4A2 |
| Chromosome | 7q34 |
| Protein Type | Anion antiporter (Cl⁻/HCO₃⁻ exchanger) |
| Function | is a critical membrane transport protein that mediates the electroneutral exchange of chloride (Cl⁻) and bicarbonate (HCO₃⁻) ions across cell membranes. |
| Primary Expression | neurons, astrocytes, and other supporting cells, where it contributes to the precise regulation of intracellular and extracellular pH |
| Molecular Weight | ~110 kDa |
| Amino Acids | 1035 aa |
| GeneCards | SLC4A2 |
| Human Protein Atlas | SLC4A2 |
| Gene Name | Solute Carrier Family 4 Member 2 |
| Alternate Names | AE2, Anion Exchanger 2, Band 3-like protein |
| Protein Size | 1035 amino acids |
| Topology | Multi-pass transmembrane (13-14 transmembrane segments) |
| Tissue | Expression Level |
| Stomach | Highest |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |