| Gene Symbol | SLC6A5 |
| Aliases | Glycine Transporter 1 |
| Chromosome | 11p15.5 |
| Protein Type | Receptor |
| Function | encodes a 12-transmembrane-domain protein of approximately 635 amino acids. |
| Primary Expression | astrocytes and endothelial cells of the blood-brain barrier |
| Amino Acids | 635 aa |
| GeneCards | SLC6A5 |
| Human Protein Atlas | SLC6A5 |
| Disorder | Therapeutic Rationale |
| Schizophrenia | GlyT1 inhibition increases glycine for NMDA co-agonism |
| Stroke/TBI | GlyT1 inhibition reduces excitotoxicity |
| Hyperekplexia | Gene therapy to restore transport |
| ADHD | GlyT1 modulators for prefrontal function |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |