gene 2,683 words KG: SMARCA2
Contents

SMARCA2 (BRM)

🧬 Gene Info
Gene SymbolSMARCA2
Full NameSWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 2
AliasesBAF155
Chromosome9p24.3
Protein TypeEnzyme
Functionencodes an ATP-dependent chromatin remodeling enzyme that serves as the catalytic subunit of the SWI/SNF (BAF) complex.
Molecular Weight175 kDa
Amino Acids447 aa
Exons35
UniProt ID[P51531](https://www.uniprot.org/uniprot/P51531)
Ensembl IDENSG00000080503
GeneCardsSMARCA2
Human Protein AtlasSMARCA2
ncBAF (non-canonical BAF)Contains BRM (but not BRG1) along with BRD9 and GLTSCR1. This complex is particularly important for neuron-specific gene regulation.
PBAF (polybromo BAF)Requires BRG1 rather than BRM, but can incorporate BRM under certain conditions.
Associated Diseasesneurodegeneration
DatabasesGeneCardsNCBI GeneHPASTRING

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