gene 1,476 words KG: SPG26 2026-03-26
kind:genesection:genesstate:published
Contents

SPG26 Gene - Bile Acid CoA: Amino Acid N-Acyltransferase

🧬 Gene Info
Gene SymbolSPG26
Full NameBAAT (Bile Acid CoA: Amino Acid N-Acyltransferase)
Chromosome12q21.31
Protein TypeEnzyme
FunctionThis enzymatic reaction occurs in the liver peroxisomes and requires
Primary Expressionmultiple tissues with varying levels:
Amino Acids524 aa
UniProt ID[Q8N6K6](https://www.uniprot.org/uniprotkb/Q8N6K6/entry)
GeneCardsSPG26
Human Protein AtlasSPG26
Associated Diseasesneurodegeneration
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (4)

Selective Acid Sphingomyelinase Modulation Therapy
Score: 0.65
CYP46A1 Overexpression Gene Therapy
Score: 0.63
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.45
Biorhythmic Interference via Controlled Sleep Oscillations
Score: 0.41

Related Analyses (3)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (13)

Animal Model Comparison for Neurodegenerative Disease Therap
clinical · proposed · Score: 0.40
Endocannabinoid System Dysfunction Validation in Parkinson's
clinical · proposed · Score: 0.40
ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40
Glymphatic-Circadian Axis Enhancement Therapy for Parkinson'
clinical · proposed · Score: 0.40
Gut Microbiome-Derived Metabolites in Alpha-Synuclein Propag
clinical · proposed · Score: 0.40

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in