| Gene Symbol | STX10 |
| Full Name | Syntaxin 10 |
| Chromosome | 17p13.1 |
| Function | is a tail-anchored protein localized primarily to the Golgi apparatus, where it participates in intracellular trafficking pathways that are critical for proper protein sorting, processing, and secr... |
| Subcellular Localization | the Golgi apparatus where it mediates membrane fusion events essential for protein trafficking and secretion. The protei |
| Amino Acids | 60 aa |
| UniProt ID | [Q9Y258](https://www.uniprot.org/uniprot/Q9Y258) |
| Ensembl ID | ENSG00000169933 |
| GeneCards | STX10 |
| Human Protein Atlas | STX10 |
| N-terminal regulatory domain | Consists of three α-helices that can fold back onto the SNARE motif, regulating SNARE complex formation (open/closed conformation) |
| SNARE motif | Central region of approximately 60 amino acids containing multiple heptad repeats that form the core of the SNARE complex |
| Transmembrane anchor | C-terminal membrane-spanning domain that anchors the protein to the Golgi membrane |
| Length | Approximately 215 amino acids |
| Phosphorylation | Regulatory phosphorylation affects SNARE complex assembly |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsNCBI GeneHPASTRING |
No AI portrait yet
No comments yet. Be the first to comment!