| Gene Symbol | STX1B |
| Full Name | Syntaxin-1B |
| Chromosome | 16p11.2 |
| Function | The STX1B gene encodes the Syntaxin-1B, a protein involved in synaptic function, axonal transport, and neuronal signaling. |
| Primary Expression | various brain reg |
| Amino Acids | 288 aa |
| UniProt ID | P61264 |
| NCBI Gene ID | 11275 |
| Ensembl ID | ENSG00000199330 |
| OMIM | 616715 |
| GeneCards | STX1B |
| Human Protein Atlas | STX1B |
| N-terminal Domain (Habc domain) | This regulatory domain folds back onto the SNARE motif in an autoinhibitory conformation, regulating the protein's availability for SNARE complex formation[@rizo2018]. |
| SNARE Motif | A central coiled-coil domain of approximately 60 residues that participates in the formation of the ternary SNARE complex with SNAP-25 and VAMP2[@sutton2018]. |
| Transmembrane Anchor | A C-terminal transmembrane domain that anchors Syntaxin-1B to the presynaptic plasma membrane[@galli2016]. |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsHPASTRING |
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