| Gene Symbol | SYT1 |
| Full Name | Synaptotagmin 1 |
| Chromosome | 12q21.1 |
| Function | Synaptotagmin 1 is a presynaptic vesicular protein that functions as the calcium sensor for fast neurotransmitter release |
| Primary Expression | Brain (cortex, hippocampus, basal ganglia, cerebellum), spinal cord |
| Amino Acids | 421 aa |
| Pathways | Apoptosis, Autophagy, autophagy pathway, oxidative stress response |
| UniProt ID | P21579 |
| NCBI Gene ID | 6858 |
| Ensembl ID | ENSG00000130147 |
| OMIM | 185580 |
| GeneCards | SYT1 |
| Human Protein Atlas | SYT1 |
| Protein Class | Calcium-binding synaptic vesicle protein |
| SNARE complex (syntaxin-1A, SNAP-25, VAMP2) | Calcium-triggered fusion machinery |
| Associated Diseases | Alzheimer, neurodegeneration |
| Known Drugs/Compounds | rapamycin |
| Interactions | ACTB, JUN, ATG7, MAP2, SNAP25, CTSB |
| KG Connections | 188 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
No comments yet. Be the first to comment!
No comments yet. Be the first to comment!