| Gene Symbol | SYNE1 |
| Full Name | Spectrin Repeat Containing Nuclear Envelope Protein 1 |
| Aliases | Page for SYNE1 Gene |
| Chromosome | 6q25.1 |
| Function | SYNE1 (Spectrin Repeat Containing Nuclear Envelope Protein 1) encodes nesprin-1, a giant protein involved in nuclear envelope organization and cytoskeletal linkages |
| Molecular Weight | 879 kDa |
| UniProt ID | Q8NF91 |
| NCBI Gene ID | 23345 |
| Ensembl ID | ENSG00000188352 |
| OMIM | 608441 |
| GeneCards | SYNE1 |
| Human Protein Atlas | SYNE1 |
| N-terminal actin-binding domain | Binds γ-actin and β-actin |
| Spectrin repeats | 56-74 spectrin repeats forming a flexible rod domain |
| Nuclear envelope targeting domain | KASH domain for nuclear membrane localization |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsHPASTRING |
No AI portrait yet
No comments yet. Be the first to comment!