gene 1,531 words KG: UBXD2
Contents

UBXD2 (UBXN6) — UBX Domain Containing 2

🧬 Gene Info
Gene SymbolUBXD2
Full NameUBX domain containing 2
Chromosome9q34.3
FunctionERAD adaptor, VCP/p97 regulator
Primary Expressionmost human tissues, with highest expression in brain, heart, and skeletal muscle
Subcellular Localizationaggresomes, which are aggregates of misfolded proteins, suggesting a role in aggregate clearance[@chitnus2021]
Amino Acids350 aa
Exons6
UniProt IDQ9Y5X5
NCBI Gene ID10277
Ensembl IDENSG00000130244
GeneCardsUBXD2
Human Protein AtlasUBXD2
Aggresome TargetingUBXD2 can localize to aggresomes, which are aggregates of misfolded proteins, suggesting a role in aggregate clearance[@chitnus2021]
Autophagy RegulationThe protein interacts with autophagy receptors and may contribute to selective autophagy pathways[@gao2023]
Associated Diseasesneurodegeneration
DatabasesGeneCardsHPASTRING

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