| Gene Symbol | UBXD3 |
| Full Name | UBX Domain Containing 3 |
| Chromosome | 13q14.2 |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Primary Expression | Ubiquitous, brain enriched |
| Amino Acids | 372 aa |
| Exons | 9 |
| UniProt ID | [Q9H6X7](https://www.uniprot.org/uniprot/Q9H6X7) |
| Ensembl ID | ENSG00000125124 |
| GeneCards | UBXD3 |
| Human Protein Atlas | UBXD3 |
| N-terminal Region | Contains potential regulatory sequences including serine/threonine phosphorylation sites |
| Coiled-coil Regions | Mediate homodimerization or heterodimerization with other UBX proteins |
| ER-associated Degradation (ERAD) | UBXD3 interfaces with the VCP/p97 complex to extract misfolded proteins from the endoplasmic reticulum for proteasomal degradation |
| Ubiquitin-Proteasome System | Acts as a co-factor for VCP/p97-mediated protein extraction and degradation |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsNCBI GeneHPASTRING |
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