| Gene Symbol | VPS53 |
| Chromosome | 17p13.1 |
| Function | VPS53 (Vacuolar Protein Sorting 53 Homolog) is a component of the HOPS (Homotypic fusion and Vacuolar Protein Sorting) complex, which plays a critical role in lysosomal trafficking and autophagy. |
| Primary Expression | neurons and glial cells, with high expression in the cerebral cortex, [hippocampus](/brain-regions/hippo |
| Molecular Weight | 79 kDa |
| Amino Acids | 672 aa |
| Ensembl ID | ENSG00000156502 |
| GeneCards | VPS53 |
| Human Protein Atlas | VPS53 |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |