gene 1,515 words KG: XRCC7 2026-03-27
kind:genesection:genesstate:published
Contents

XRCC7 (DNA-PKcs) - DNA-Dependent Protein Kinase Catalytic Subunit

🧬 Gene Info
Gene SymbolXRCC7 (DNA-PKcs)
Full NameX-Ray Repair Cross-Complementing 7 / DNA-PK Catalytic Subunit
AliasesDNA-PKcs
Chromosome8q24.21
Functionis a central component of the non-homologous end joining (NHEJ) pathway, the predominant mechanism for repairing DNA double-strand breaks (DSBs) in mammalian cells.
Primary Expressionvirtually all cell types:
Molecular Weight~469 kDa
Amino Acids4128 aa
UniProt IDP78527
NCBI Gene ID5591
Ensembl IDENSG00000137413
OMIM604743
Protein Length4128 amino acids
Protein ClassSerine/threonine protein kinase
Associated Diseasesneurodegeneration
DatabasesGeneCardsHPASTRING

Knowledge Graph