gene 3,651 words KG: ZFYVE26 2026-03-24
kind:genesection:genesstate:published
Contents

ZFYVE26 Gene

🧬 Gene Info
Gene SymbolZFYVE26
AliasesSPG15
Chromosome14q24.3
Functionis a gene encoding a critical autophagy protein that plays essential roles in cellular protein homeostasis and organelle quality control.
Subcellular Localizationcytoplasmic membranes, particularly autophagosomes and late endosomes, where it serves as a scaffold for autophagy-relat
Molecular Weight235 kDa
Amino Acids100 aa
GeneCardsZFYVE26
Human Protein AtlasZFYVE26
LC3/GABARAPDirect binding
p62/SQSTM1Complex formation
NBR1Complex formation
VPS34 (PIK3C3)Regulatory
ESCRT componentsComplex formation
ATG14LComplex formation
Associated Diseasesneurodegeneration
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph