| Gene Symbol | GPM6B |
| Aliases | GPM6BPROTEIN |
| Function | Gpm6B Protein is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes. |
| Molecular Weight | 32 kDa |
| Amino Acids | 278 aa |
| GeneCards | GPM6B |
| Human Protein Atlas | GPM6B |
| Four transmembrane helices | Spanning the lipid bilayer |
| Two extracellular loops | Heavily glycosylated, involved in protein-protein interactions |
| Two intracellular loops | Contain potential phosphorylation sites |
| N-terminal signal sequence | Directs membrane insertion |
| C-terminal PDZ-binding motif | Enables scaffolding protein interactions |
| Cerebellum | Expression in Purkinje cells and granule cells |
| Basal ganglia | Detected in striatum and substantia nigra |
| Thalamus and hypothalamus | Moderate expression |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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