gene 2,092 words KG: HNRNPUL2
Contents

HNRNPUL2 Gene

🧬 Gene Info
Gene SymbolHNRNPUL2
Chromosome19q13.43
Functionis a nuclear matrix protein that belongs to the hnRNP U family.
Primary Expressionhuman tissues, with particularly high expression in neuronal nuclei
Amino Acids640 aa
GeneCardsHNRNPUL2
Human Protein AtlasHNRNPUL2
N-terminal SAP domainInvolved in DNA/RNA binding and nuclear matrix attachment
Central glycine-rich regionFacilitates protein-protein interactions
C-terminal RGG repeatsRNA-binding motifs involved in RNA granule formation
Alternative splicing regulationModulates inclusion or exclusion of specific exons
RNA stabilityBinds to specific RNA sequences to regulate mRNA half-life
RNA transportFacilitates transport of mRNAs from nucleus to cytoplasm
BrainParticularly in the cerebral cortex, hippocampus, and spinal cord motor neurons
TestisHigh expression in spermatogonia and spermatocytes
Associated Diseasesneurodegeneration
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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