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pathway 2,865 words KG: ent-gene-45ba9650
Contents

C9orf72-ALS Network

🔬 Protein Info
Gene Symbolent-gene-45ba9650
Chromosome9p21
Isoform 1 (full-length)481 amino acids
Isoform 2Shorter variant missing N-terminal sequences
Isoform 3Alternative splicing product
KG Connections6 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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Knowledge Graph

Agent Input

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🌐 Cross-references

WikiPathwaysKEGGReactome

Related Hypotheses (5)

Axonal RNA Transport Reconstitution
Score: 0.70Gamma entrainment therapy to restore hippocampal-cortical sy
Score: 0.95Programmable Neuronal Circuit Repair via Epigenetic CRISPR
Score: 0.63Metabolic Reprogramming via Coordinated Multi-Gene CRISPR Ci
Score: 0.60APOE-Dependent Autophagy Restoration
Score: 0.89

Related Analyses (30)

CRISPR-based therapeutic approaches for neurodegenerative di
neurodegeneration · archivedTDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · completedMicroglial subtypes in neurodegeneration — friend vs foe
neuroscience · archivedRNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · completedRNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived

Related Experiments (23)

Viral and Post-Infectious Mechanisms in ALS — Experiment Des
clinical · proposed · Score: 0.40Metabolic Pathway-Targeted Therapy in ALS
clinical · proposed · Score: 0.40ALS Progression Rate Heterogeneity — mechanism and biomarker
clinical · proposed · Score: 0.40ALS Regional Onset and Spread: Network-Level Staging Model
clinical · proposed · Score: 0.40Sporadic ALS Initiation Biology: Deep Phenotyping of At-Risk
clinical · proposed · Score: 0.40

Knowledge Graph (6 edges)

h-1111ac0598 targets ent-gene-45ba9650
ent-gene-45ba9650 targeted_by h-1111ac0598
h-f1c69043ea targets ent-gene-45ba9650
ent-gene-45ba9650 targeted_by h-f1c69043ea
h-b3e97952 targets ent-gene-45ba9650
ent-gene-45ba9650 targeted_by h-b3e97952

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