disease 2,283 words KG: ent-dise-6a53f4d8
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Myotonic Dystrophy

Disease Info
Mild DM150-150 repeats
Classic DM1100-500 repeats
Congenital/Childhood DM1750-2000+ repeats[@nih]
Normal< 26 CCTG repeats
Affected75-11,000+ repeats[@biomedical]
Proximal muscle weaknessQuadriceps and hip flexors primarily affected[@biomedical]
MyotoniaLess prominent, often subclinical[@biomedical]
Less severe cardiac involvementCompared to DM1[@biomedical]
Later onsetTypically fourth decade or later[@biomedical]
Minimal cognitive impairmentCompared to DM1[@biomedical]
Painless myalgiasMuscle pain, especially in thighs[@biomedical]### Inheritance
DatabasesOMIMOrphanetClinicalTrialsPubMed

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