gene 1,289 words KG: NUP62
Contents

NUP62 — Nucleoporin 62

🧬 Gene Info
Gene SymbolNUP62
Full NameNucleoporin 62
Chromosome19q13.33
FunctionThis trimeric complex forms the constriction ring of the NPC and is essential for
Molecular Weight62 kDa
Amino Acids522 aa
UniProt IDP37198
NCBI Gene ID23636
Ensembl IDENSG00000213024
OMIM605815
GeneCardsNUP62
Human Protein AtlasNUP62
Selective permeabilityCreating the FG-hydrogel that discriminates cargo by size and transport receptor binding
NPC biogenesisRequired for de novo NPC assembly during interphase and post-mitotic NPC reconstitution
NPC maintenanceTurnover and replacement of damaged nucleoporins in long-lived neurons
Associated DiseasesHuntington's Disease, Infantile Bilateral Striatal Necrosis
DatabasesGeneCardsHPASTRING

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