disease 1,619 words KG: ent-dise-a0dee463 2026-03-19
kind:diseasesection:diseasesstate:published
Contents

Opsoclonus-Myoclonus Syndrome

Disease Info
Cartilage-related antigen (CRMP5)Also known as CV2, this antibody is associated with paraneoplastic neurological syndromes
GAD65 antibodiesGlutamic acid decarboxylase, though less common in OMS
Surface membrane antibodiesIncluding those targeting voltage-gated calcium channel subunits
TremorIntention tremor and postural tremor
DysmetriaPast-pointing on finger-to-nose testing
DysarthriaSlurred speech due to cerebellar involvement
NystagmusJerky nystagmus may accompany opsoclonus
Cognitive and behavioral changesIrritability, attention deficits, sleep disturbances
HypotoniaDecreased muscle tone is common in children
DatabasesOMIMOrphanetClinicalTrialsPubMed

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