| Gene Symbol | ADAR2 |
| Aliases | ADAR2PROTEIN |
| Function | Adar2 Protein is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes. |
| Subcellular Localization | signal (NLS)**: Directs protein to the nucleus - **Zinc-binding motif**: Critica |
| Molecular Weight | 80 kDa |
| GeneCards | ADAR2 |
| Human Protein Atlas | ADAR2 |
| Deaminase domain | Catalytic domain that performs A-to-I editing |
| Nuclear localization signal (NLS) | Directs protein to the nucleus |
| Zinc-binding motif | Critical for catalytic activity |
| GluA2 editing | Converts Q/R site from CAG (glutamine) to CIG (arginine) in GRIA2 pre-mRNA, essential for preventing Ca2+ influx |
| Serotonin receptor editing | Modifies 5-HT2C receptor (HTR2C) mRNA |
| RNA interference | Editing can alter miRNA targeting |
| Viral defense | A-to-I editing affects viral RNA recognition |
| Epigenetic effects | Inosine is read as guanosine by cellular machinery |
| Associated Diseases | Glioma Grade |
| KG Connections | 1 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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