protein 1,042 words KG: ATAXIN10
Contents

Ataxin-10 Protein

🔬 Protein Info
Gene SymbolATAXIN10
Full NameAtaxin-10
Chromosome22q13.31.
Protein FamilyAtaxin family (non-aggregating)
Functionis an important component in the neurobiology of neurodegenerative diseases.
Primary ExpressionHigh in cerebellum (Purkinje cells), cerebral cortex, brainstem
Subcellular Localizationand export signals for nucleocytoplasmic shuttling - **No known catalytic domain
Molecular Weight~47 kDa (420 amino acids)
Amino Acids420 aa
UniProt IDQ9UBB6
GeneCardsATAXIN10
Human Protein AtlasATAXIN10
HEAT repeats6-7 HEAT (Huntingtin, Elongation factor 3, PP2A, TOR1) repeat motifs throughout the protein
Alpha-helical contentPredominantly alpha-helical secondary structure
NLS/NES sequencesNuclear localization and export signals for nucleocytoplasmic shuttling
Associated Diseasesneurodegeneration
DatabasesGeneCardsNCBI GeneHPASTRING

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