| Gene Symbol | ATAXIN3 |
| Aliases | ATAXIN3PROTEIN |
| Protein Family | Josephin family (deubiquitinating enzymes) |
| Protein Type | Enzyme |
| Function | is a deubiquitinating enzyme encoded by the ATXN3 gene. |
| Molecular Weight | 42 kDa |
| UniProt ID | P54252 |
| GeneCards | ATAXIN3 |
| Human Protein Atlas | ATAXIN3 |
| Modulation of stress response pathways | Ataxin-3 regulates NF-κB signaling through deubiquitination of IκB kinase (IKK), controlling inflammatory responses and apoptotic threshold in neurons under cellular stress conditions[^5]. |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsNCBI GeneHPASTRING |
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