protein 683 words KG: ATXN7 2026-03-22
kind:proteinsection:proteinsstate:published
Contents

Ataxin-7 (ATXN7)

🔬 Protein Info
Gene SymbolATXN7
AliasesAtaxin-7
Chromosome3p
Protein TypeTransferase
Functionencodes ataxin-7, a nuclear protein that serves as a structural and functional subunit of SAGA-family transcriptional coactivator complexes
Molecular Weight95 kDa
UniProt IDO15265
GeneCardsATXN7
Human Protein AtlasATXN7
N-terminal polyglutamine tractCAG repeat region (normal <19; pathogenic >35)
Sgf11-interacting domainanchors ataxin-7 to the SAGA complex
Nuclear localization signalsmultiple NLS motifs
Splice variantsmultiple isoforms with different domain compositions
Rod and cone gene expressionSAGA regulates phototransduction genes
Photoreceptor survivalMaintains retinal gene expression programs
Associated Diseasesneurodegeneration
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph