| Gene Symbol | BETAGALACTOSIDASE |
| Aliases | BETAGALACTOSIDASE |
| Each subunit | ~60 kDa |
| Active site | Contains a glutamate residue as the catalytic nucleophile |
| Glycosylation | Heavily N-glycosylated for proper lysosomal targeting |
| Lysosomal distension | Swollen lysosomes |
| Neuronal dysfunction | Impaired synaptic transmission |
| Progressive neurodegeneration | Cognitive decline, motor impairment |
| Axonal degeneration | White matter abnormalities |
| Parkinson's Disease | GM1 may interact with α-synuclein |
| Alzheimer's Disease | Altered ganglioside metabolism |
| General | Lysosomal dysfunction is a common feature |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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