protein 647 words KG: BETAIIISPECTRIN
Contents

βIII-Spectrin

🔬 Protein Info
Gene SymbolBETAIIISPECTRIN
AliasesBETAIIISPECTRIN
Subcellular Localization</th><td>Cytoskeleton, plasma membrane</td></tr>
N-terminal actin-binding domainBinds to junctional complexes
Spectrin repeat region17 spectrin repeats (α-helical)
PH domainPhosphoinositide binding
C-terminal domainDimerization and membrane association
Spectrin repeats17-20 triple-helical repeats
EF-hand calcium-binding motifsRegulation of stability
Ankyrin-binding siteMembrane anchoring
Phosphorylation sitesMultiple regulatory sites
Membrane skeletonStabilizes plasma membrane
Protein anchoringLinks membrane proteins to actin
Synapse organizationMaintains postsynaptic density
Organelle traffickingVesicular transport support
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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