protein 981 words KG: BMFPROTEIN
Contents

BMF Protein

🔬 Protein Info
Gene SymbolBMF
Full NameBcl-2 Modifying Factor
AliasesBMFPROTEIN
Chromosome15q14
Functionis an important component in the neurobiology of neurodegenerative diseases.
Primary Expressionvarious tissues with highest expression in:
Subcellular LocalizationRelease from cytoskeletal sequestration is a key regulatory step
Amino Acids184 aa
UniProt ID[Q9Y3T5](https://www.uniprot.org/uniprot/Q9Y3T5)
Ensembl IDENSG00000108298
GeneCardsBMF
Human Protein AtlasBMF
N-terminal regionContains the BH3 domain (amino acids 101-127), the critical functional motif for binding to anti-apoptotic Bcl-2 proteins
Flexible N-terminusRegulatory region that allows for post-translational modifications and protein interactions
Hydrophobic C-terminusInvolved in mitochondrial membrane association
Associated Diseasesneurodegeneration
DatabasesGeneCardsNCBI GeneHPASTRING

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