protein 970 words KG: CAMK1PROTEIN 2026-03-28
kind:proteinsection:proteinstopic:alzheimerstopic:parkinsons
Contents

CaMK1 Protein

🔬 Protein Info
Gene SymbolCAMK1PROTEIN
Protein TypeKinase
Functionis a serine/threonine protein kinase that plays critical roles in neuronal signaling, synaptic plasticity, and memory formation.
Primary Expressionvarious tissues
Subcellular Localizationkinase is activated by binding of calcium/calmodulin to its regulatory domain, w
Molecular Weight42 kDa
Amino Acids374 aa
GeneCardsCAMK1PROTEIN
Human Protein AtlasCAMK1PROTEIN
CaMK1-alphaPredominant neuronal isoform
CaMK1-betaExpressed in various tissues
CaMK1-gammaTestis-specific variant
Phosphorylation of Synaptic ProteinsPhosphorylates proteins involved in synaptic vesicle release and neurotransmitter release[@skelding2011]
AMPA Receptor RegulationModulates AMPA receptor trafficking and function during long-term potentiation (LTP)
NMDA Receptor ModulationRegulates NMDA receptor channel properties and downstream signaling
Associated Diseasesneurodegeneration
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph