protein 1,469 words KG: CATHEPSINDPROTEIN
Contents

CATHEPSINDPROTEIN Protein

🔬 Protein Info
Gene SymbolCATHEPSIND
AliasesCATHEPSINDPROTEIN
Chromosome1p32.2
Protein TypeProtease
Functionis an important component in the neurobiology of neurodegenerative diseases.
Subcellular Localizationprimarily to lysosomes in neurons and glia
Molecular Weight52 kDa
Amino Acids412 aa
GeneCardsCATHEPSIND
Human Protein AtlasCATHEPSIND
N-terminal DomainContains the propeptide and first part of the heavy chain
C-terminal DomainContains the second half of the heavy chain and light chain
Active SiteTwo Asp residues positioned in a cleft between the two lobes
Glycosylation SitesN-linked carbohydrates important for stability and trafficking
Associated Diseasesneurodegeneration
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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