| Gene Symbol | CATHEPSINL |
| Full Name | Cathepsin L |
| Protein Family | Papain family (C1A) |
| Protein Type | Protease |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Molecular Weight | 33 kDa (proenzyme), 25 kDa (mature enzyme) |
| UniProt ID | P07711 |
| GeneCards | CATHEPSINL |
| Human Protein Atlas | CATHEPSINL |
| Signal peptide | Targets the protein to the secretory pathway |
| Propeptide | Inhibits activity until reaching the lysosome |
| Mature enzyme | Active protease following propeptide cleavage |
| Active site | Catalytic cysteine (C25), histidine (H163), and asparagine (N183) |
| Occluding loop | Regulates substrate access |
| Two disulfide bonds | Stabilize the structure |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsNCBI GeneHPASTRING |
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