| Gene Symbol | CAV12 |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Amino Acids | 000 aa |
| GeneCards | CAV12 |
| Human Protein Atlas | CAV12 |
| Primary Structure | Single polypeptide of ~2,000 amino acids |
| Domain Organization | Four homologous domains (I-IV), each containing 6 transmembrane segments |
| Voltage sensor | S4 segments with positively charged residues |
| Dihydropyridine binding site | Between domains III and IV |
| CaM binding domain | IQ motif in C-terminus |
| Auxiliary Subunits | α2δ, β, γ subunits modulate function |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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