protein 644 words KG: CDR2PROTEIN 2026-03-23
kind:proteinsection:proteinsstate:published
Contents

CDR2 Protein

🔬 Protein Info
Gene SymbolCDR2
AliasesCerebellar Degeneration-Related Protein 2
Chromosome12p13
Protein TypeGene
Functionis a cytoplasmic antigen that serves as the primary autoantibody target in paraneoplastic cerebellar degeneration (PCD), a rare autoimmune disorder affecting the cerebellum.
Primary Expressionneural tissue
Molecular Weight55 kDa
Amino Acids520 aa
GeneCardsCDR2
Human Protein AtlasCDR2
Anti-CDR2 AntibodiesAutoimmune markers in paraneoplastic neurological syndromes
Paraneoplastic Neurological SyndromesCancer-associated neuronal dysfunction conditions
Cerebellar NeurodegenerationPrimary pathological outcome of CDR2 dysfunction
Calcium SignalingKey neuronal process regulated by CDR2
Mitochondrial DysfunctionAssociated consequence of CDR2 impairment
Associated Diseasesneurodegeneration
KG Connections2 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph