protein 943 words KG: CHASERPROTEIN 2026-03-21
kind:proteinsection:proteinsstate:published
Contents

CYP11A1 Protein (Cholesterol Side-Chain Cleavage Enzyme)

🔬 Protein Info
Gene SymbolCYP11A1
Full NameCytochrome P450 Family 11 Subfamily A Member 1
AliasesPage for CYP11A1 Gene (CHASER)
Chromosome15q24.2
Protein FamilyCytochrome P450 family
Protein TypeEnzyme
Functionis a critical enzyme in steroid biosynthesis and neurosteroid production.
Primary Expressionneurons and glial cells, where it contributes to local neurosteroid synthesis
Subcellular LocalizationMitochondrial inner membrane
Molecular Weight56 kDa
UniProt IDP05093
NCBI Gene ID1583
Ensembl IDENSG00000140359
OMIM118485
GeneCardsCYP11A1
Human Protein AtlasCYP11A1
Associated Diseasesneurodegeneration
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (8)

Cholesterol-CRISPR Convergence Therapy for Neurodegeneration
Score: 0.48
Membrane Cholesterol Gradient Modulators
Score: 0.52
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.51
Lysosomal Enzyme Trafficking Correction
Score: 0.49
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.42

Related Analyses (9)

Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
What are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · archived

Related Experiments (13)

Animal Model Comparison for Neurodegenerative Disease Therap
clinical · proposed · Score: 0.40
Endocannabinoid System Dysfunction Validation in Parkinson's
clinical · proposed · Score: 0.40
ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40
Glymphatic-Circadian Axis Enhancement Therapy for Parkinson'
clinical · proposed · Score: 0.40
Gut Microbiome-Derived Metabolites in Alpha-Synuclein Propag
clinical · proposed · Score: 0.40

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in