| Gene Symbol | CHRNA1 |
| Full Name | Cholinergic Receptor Nicotinic Alpha Subunit 1 |
| Chromosome | 2q31.1 |
| Function | CHRNA1 is a key component of the muscle-type nAChR, a pentameric ligand-gated ion channel[@changeux2020]: |
| Subcellular Localization | ** | Plasma membrane (ligand-gated ion channel) | |
| Molecular Weight | 55 kDa |
| UniProt ID | P30530 |
| NCBI Gene ID | 1135 |
| Ensembl ID | ENSG00000138435 |
| OMIM | 100710 |
| GeneCards | CHRNA1 |
| Human Protein Atlas | CHRNA1 |
| Extracellular N-terminal domain | Contains the acetylcholine binding site |
| Cys-loop motif | Characteristic of the Cys-loop receptor family |
| Four transmembrane domains (M1-M4) | Form the ion channel pore |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsHPASTRING |
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