| Gene Symbol | CHRNA2 |
| Full Name | Cholinergic receptor nicotinic alpha 2 subunit |
| Aliases | Cholinergic Receptor Nicotinic Alpha 2 |
| Chromosome | 8p21 |
| Protein Family | Cys-loop receptor family; Nicotinic acetylcholine receptor |
| Protein Type | Receptor |
| Function | is a member of the Cys-loop receptor superfamily, which also includes GABAₐ, glycine, and 5-HT₃ receptors. |
| Primary Expression | both the central and peripheral nervous systems, where they mediate fast synaptic transmission and modulate neuronal excitability |
| Subcellular Localization | Plasma membrane (neuronal ligand-gated ion channel) |
| Molecular Weight | ~56 kDa |
| UniProt ID | P43681 |
| Ensembl ID | ENSG00000120288 |
| GeneCards | CHRNA2 |
| Human Protein Atlas | CHRNA2 |
| Protein Name | Nicotinic acetylcholine receptor subunit alpha-2 |
| Associated Diseases | neurodegeneration |
| KG Connections | 14 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |