protein 1,058 words KG: CLCN5PROTEIN
Contents

ClC-5 Chloride Channel

🔬 Protein Info
Gene SymbolCLCN5PROTEIN
Full NameClC-5 Chloride Channel
ChromosomeXp11.23
Protein FamilyCLC chloride channel family
Protein TypeChannel
Functionis a chloride channel primarily expressed in kidney proximal tubules and intestinal epithelium.
Primary Expressionkidney proximal tubules and intestinal epithelium
Molecular Weight~83 kDa
Exons11
UniProt IDP51795
OMIM300009
GeneCardsCLCN5PROTEIN
Human Protein AtlasCLCN5PROTEIN
Associated DiseasesDent's Disease, Hypercalciuria, Proximal Tubule Dysfunction
KG Connections4 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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Related Hypotheses (6)

Mechanosensitive Ion Channel Reprogramming
Score: 0.70
Lysosomal Calcium Channel Modulation Therapy
Score: 0.70
Aquaporin-4 Polarization Enhancement via TREK-1 Channel Modu
Score: 0.67
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.62

Related Analyses (9)

Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived
TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived

Related Experiments (12)

Animal Model Comparison for Neurodegenerative Disease Therap
clinical · proposed · Score: 0.40
Endocannabinoid System Dysfunction Validation in Parkinson's
clinical · proposed · Score: 0.40
Glymphatic-Circadian Axis Enhancement Therapy for Parkinson'
clinical · proposed · Score: 0.40
Gut Microbiome-Derived Metabolites in Alpha-Synuclein Propag
clinical · proposed · Score: 0.40
Neural Oscillation Dysfunction Validation in Parkinson's Dis
clinical · proposed · Score: 0.40

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in

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