| Gene Symbol | CMETPROTEIN |
| Function | is a heterodimeric transmembrane protein consisting of |
| Amino Acids | 500 aa |
| GeneCards | CMETPROTEIN |
| Human Protein Atlas | CMETPROTEIN |
| Extracellular α-chain | Sema domain (~500 aa) containing the HGF binding site |
| β-chain | Transmembrane domain with intracellular tyrosine kinase domain |
| Sema Domain | Semaphorin-like fold responsible for ligand binding and receptor dimerization |
| PSI Domain | Plexin-Semaphorin-Integrin homology region |
| IPT Domain | Immunoglobulin-like fold in the extracellular region |
| Kinase Domain | Catalytic tyrosine kinase (~300 aa) with regulatory activation loop |
| Process | Pathway |
| Survival | PI3K/AKT → BAD phosphorylation |
| Proliferation | RAS/MAPK → ERK activation |
| Migration | RAC/CDC42 → cytoskeletal reorganization |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |