| Gene Symbol | COMPLEXIN |
| Protein Family | Complexin family |
| Function | Synaptic vesicle fusion regulation |
| Primary Expression | excitatory neurons, essential for fast synchronous neurotransmitter release
- CPLX2: Expressed in both excitatory and inhibit |
| Molecular Weight | ~15-17 kDa per monomer |
| UniProt ID | Q9R0E5 (CPLX1), Q96A56 (CPLX2), Q8WV92 (CPLX3), Q7Z594 (CPLX4) |
| GeneCards | COMPLEXIN |
| Human Protein Atlas | COMPLEXIN |
| Protein Name | Complexin |
| Gene Symbols | CPLX1, CPLX2, CPLX3, CPLX4 |
| Location | Presynaptic terminal |
| Structure | Alpha-helical bundle |
| Target | Approach |
| Complexin modulators | Small molecules to enhance clamping |
| SNARE complex stabilization | Peptide-based approaches |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsNCBI GeneHPASTRING |