| Gene Symbol | COMPLEXIN |
| Full Name | 1 Protein (CPLX1) |
| Protein Family | Complexin family |
| Function | Synaptic vesicle fusion regulation |
| Primary Expression | excitatory neurons, essential for fast synchronous neurotransmitter release - CPLX2: Expressed in both excitatory and inhibit |
| Molecular Weight | 17 kDa |
| UniProt ID | Q9R0E5 (CPLX1), Q96A56 (CPLX2), Q8WV92 (CPLX3), Q7Z594 (CPLX4) |
| GeneCards | COMPLEXIN |
| Human Protein Atlas | COMPLEXIN |
| N-terminal activating segment | supports efficient calcium-triggered release. |
| Accessory helix | contributes to clamping of premature fusion. |
| Central helix | high-affinity binding to assembled SNARE bundles. |
| C-terminal segment | supports membrane association and spatial positioning. |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsNCBI GeneHPASTRING |
No AI portrait yet
No comments yet. Be the first to comment!