| Gene Symbol | COMPLEXIN1 |
| Aliases | COMPLEXIN1PROTEIN |
| Function | is a small synaptic protein (134 amino acids, ~15 kDa) that critically regulates neurotransmitter release by modulating SNARE complex assembly and fusion kinetics. |
| Molecular Weight | 16 kDa |
| Amino Acids | 136 aa |
| GeneCards | COMPLEXIN1 |
| Human Protein Atlas | COMPLEXIN1 |
| N-terminal domain | Membrane-interacting domain |
| Central alpha-helix | Core region that binds to SNARE complexes |
| C-terminal domain | Involved in self-association and interactions |
| SNARE complex binding | Binds to assembled SNARE complexes |
| Fusion clamp | Prevents premature fusion while allowing synchronized release |
| Calcium sensing | Modulates release probability in response to calcium |
| Synaptic vesicle dynamics | Regulates vesicle pool sizes |
| Short-term plasticity | Influences facilitation and depression |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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