| Gene Symbol | COQ8B |
| Full Name | Coenzyme Q8B (ADCK4) |
| Aliases | ubiquinone, COQ8B Protein |
| Chromosome | 19q13.2 |
| Protein Type | Enzyme |
| Function | encodes a mitochondrial protein essential for coenzyme Q (ubiquinone) biosynthesis. |
| Molecular Weight | 72.4 kDa |
| Amino Acids | 678 aa |
| UniProt ID | Q9GZX4 |
| NCBI Gene ID | 79934 |
| GeneCards | COQ8B |
| Human Protein Atlas | COQ8B |
| CoQ Complex Binding Region | The central and C-terminal regions mediate interactions with other COQ proteins (COQ3, COQ4, COQ6, COQ7, COQ9) to form the CoQ biosynthesis complex. |
| Transmembrane Regions | Multiple predicted transmembrane helices anchor COQ8B to the inner mitochondrial membrane. |
| Mitochondrial Targeting Sequence | An N-terminal amphipathic helix directs mitochondrial localization. |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsHPASTRING |
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