| Gene Symbol | CYCLINF |
| Aliases | CYCLINFPROTEIN |
| Function | Cyclin F Protein is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes. |
| GeneCards | CYCLINF |
| Human Protein Atlas | CYCLINF |
| F-box domain | For SCF complex assembly with Skp1 and Cul1 |
| Leucine-rich repeats (LRR) | Substrate recognition domain |
| Dimerization domain | Forms homodimers |
| Substrate ubiquitination | SCF^CCNF targets specific proteins for proteasomal degradation |
| Cell cycle regulation | Controls G1/S and G2/M transitions |
| DNA damage response | Targets proteins involved in DNA repair |
| Iron homeostasis | Regulates IRP2 stability, controlling cellular iron levels |
| Ribosomal biogenesis | Controls synthesis of ribosomal proteins |
| Loss of function | Reduced ubiquitination of substrate proteins |
| Protein aggregation | Mutant cyclin F forms inclusions |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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