| Gene Symbol | DNM2 |
| Aliases | Dynamin 2 |
| Chromosome | 19p13.2 |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Primary Expression | Ubiquitous, high in brain |
| Molecular Weight | 98 kDa |
| Amino Acids | 870 aa |
| UniProt ID | P50570 |
| GeneCards | DNM2 |
| Human Protein Atlas | DNM2 |
| Clathrin-Mediated Endocytosis (CME) | DNM2 is the canonical membrane fission enzyme for clathrin-coated vesicle formation [6] |
| Synaptic Vesicle Recycling | Essential for recycling synaptic vesicles after neurotransmitter release [7] |
| Receptor Internalization | Regulates surface receptor density through controlled internalization [8] |
| Cargo Selection | Interfaces with adaptors to ensure specific cargo inclusion [9] |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsNCBI GeneHPASTRING |
No AI portrait yet
No comments yet. Be the first to comment!