Contents

Dynamin-1 Protein

🔬 Protein Info

Gene Symbol	DNM1L
Full Name	Dynamin 1 Like (Dynamin-Related Protein 1)
Chromosome	12p11.21
Function	DRP1 orchestrates mitochondrial fission
Primary Expression	astrocytes and microglia
Subcellular Localization	Cytosolic, synaptic vesicles, mitochondria
Molecular Weight	~96 kDa
Pathways	Apoptosis, Mitochondrial Function, Mitophagy, Oxidative Stress
UniProt ID	Q05193
NCBI Gene ID	10059
Ensembl ID	ENSG00000087420
GeneCards	DNM1L
Human Protein Atlas	DNM1L
Protein Name	Dynamin-1
Protein Length	864 amino acids
Associated Diseases	AD, ALI, ALS, Aging, Alzheimer
Known Drugs/Compounds	rapamycin, metformin
Interactions	CANX, LGALS3, CALCOCO2, G3BP1, PEX3, SQSTM1
KG Connections	974 knowledge graph edges
Databases	GeneCards HPA STRING

Knowledge Graph