| Gene Symbol | FAM172A |
| Aliases | FAM172APROTEIN |
| Function | The protein is conserved from mammals to fish, indicating an evolutionarily important function. |
| Subcellular Localization | reported ## Role in Neurodegeneration ### Alzheimer's Disease FAM172A has bee |
| Molecular Weight | 37 kDa |
| Amino Acids | 326 aa |
| GeneCards | FAM172A |
| Human Protein Atlas | FAM172A |
| N-terminal domain | Contains predicted coiled-coil regions that may mediate protein-protein interactions |
| Central region | Low-complexity sequences with potential regulatory functions |
| C-terminal domain | Highly conserved across species, suggesting functional importance |
| Central nervous system | Expressed in various brain regions including the hippocampus, cerebral cortex, and cerebellum |
| Peripheral tissues | Highest expression in testis, with moderate levels in liver, kidney, and heart |
| Cellular localization | Primarily cytoplasmic, with some nuclear localization reported |
| Genetic associations | Genome-wide association studies (GWAS) have identified FAM172A variants associated with late-onset AD risk |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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