| Gene Symbol | FGFR |
| Full Name | 1 Protein |
| Protein Family | FGFR family, Receptor tyrosine kinase |
| Function | Fibroblast Growth Factor Receptor 1 (FGFR1) is a receptor tyrosine kinase that plays critical roles in neuronal development, survival, and plasticity. |
| Subcellular Localization | Cell surface, Endosomes (after ligand binding) |
| Molecular Weight | 92.0 kDa (FGFR1c isoform) |
| Pathways | Cell Differentiation, Cell Proliferation, Cell Survival |
| UniProt ID | P11362 |
| GeneCards | FGFR |
| Human Protein Atlas | FGFR |
| Protein Name | Fibroblast Growth Factor Receptor 1 (FGFR1) |
| Gene | FGFR1 |
| PDB | 1evs, 2cr7, 5w5j |
| Neural Development | FGFR1 is expressed in neural stem cells and progenitor cells, where it promotes proliferation, differentiation, and survival during brain development [4]. |
| Neurogenesis | FGFR1 signaling maintains adult hippocampal neurogenesis and supports neural progenitor cell pools in the subventricular zone [4]. |
| Associated Diseases | ALS |
| KG Connections | 1 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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