| Gene Symbol | FGFR1 |
| Full Name | FGFR-1 |
| Aliases | Fibroblast Growth Factor Receptor 1 |
| Chromosome | 8p11 |
| Protein Type | Protein |
| Function | FGFR1 encodes fibroblast growth factor receptor 1, a receptor tyrosine kinase that binds multiple FGF ligands (FGF1, FGF2, FGF4, etc.). |
| Primary Expression | neural stem cells, neurons, and astrocytes |
| Subcellular Localization | **: Cell surface, Endosomes (after ligand binding) |
| Pathways | MAPK, PI3K |
| UniProt ID | [P11362](https://www.uniprot.org/uniprot/P11362) |
| Ensembl ID | ENSG00000077782 |
| OMIM | 136350 |
| GeneCards | FGFR1 |
| Human Protein Atlas | FGFR1 |
| Associated Diseases | ALS, Cancer, Epilepsy, Glioblastoma, Ms |
| Interactions | FGF2, FGF21, SOD2, NOX4, SOD1, CX3CR1 |
| KG Connections | 234 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |