protein 647 words KG: FMN2PROTEIN
Contents

Formin 2 Protein

🔬 Protein Info
Gene SymbolFMN2PROTEIN
Protein FamilyFormin family, FH2 domain proteins
Functionis an important component in the neurobiology of neurodegenerative diseases.
Molecular Weight180 kDa
Amino Acids1625 amino acids
UniProt IDQ9Y2D5
GeneCardsFMN2PROTEIN
Human Protein AtlasFMN2PROTEIN
FH1 (Formin Homology 1) domainproline-rich, binds profilin and SH3 domains
FH2 (Formin Homology 2) domaindimeric actin-binding core
Dimerization domainmediates homodimerization
Regulatory regionsauto-inhibition and activation
Nucleates filamentsinitiates new actin filament formation
Elongates rapidlymaintains fast polymerization at barbed ends
Inhibits cappingprotects barbed ends from capping proteins
Associated Diseasesneurodegeneration
InteractionsCALCOCO2
KG Connections6 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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