| Gene Symbol | FZD1 |
| Aliases | FZD1PROTEIN |
| Chromosome | 7q21.13 |
| Protein Type | Gene |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Primary Expression | the brain and plays important roles in neural development, synapse formation, and plasticity |
| Subcellular Localization | Plasma membrane |
| Molecular Weight | 65 kDa |
| Pathways | Wnt signaling, Wnt, Wnt pathway |
| UniProt ID | Q9Y6R4 |
| NCBI Gene ID | 2791 |
| Ensembl ID | ENSG00000157240 |
| GeneCards | FZD1 |
| Human Protein Atlas | FZD1 |
| N-terminal cysteine-rich domain (CRD) | The extracellular CRD (~120 aa) binds Wnt ligands with high affinity. This domain contains 10 conserved cysteine residues that form disulfide bonds, creating a rigid binding pocket[@janda2012]. |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsHPASTRING |
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