protein 976 words KG: GEMIN2PROTEIN 2026-03-21
kind:proteinsection:proteinsstate:published
Contents

Gemin-2 Protein

🔬 Protein Info
Gene SymbolGem Nuclear Organelle Associated Protein 2
AliasesGEMIN2 gene in ALS and SMA
Chromosome14q13.2
Protein FamilySMN complex / Gem-associated proteins
Functionis a critical component of the SMN (Survival of Motor Neuron) complex that is essential for spliceosomal small nuclear ribonucleoprotein (snRNP) biogenesis.
Primary ExpressionUbiquitous, high in brain and spinal cord
Subcellular LocalizationNucleus (Cajal bodies), cytoplasm
Molecular Weight31.8 kDa
Gene TypeProtein coding
UniProt IDO94876
NCBI Gene ID25956
Ensembl IDENSG00000145901
OMIM609721
Protein NameGemin-2 (SIP1)
GeneGEMIN2
Associated Diseasesneurodegeneration
DatabasesGeneCardsHPASTRING

Knowledge Graph