| Gene Symbol | GEMIN5 |
| Aliases | GEMIN5PROTEIN |
| Chromosome | 14q12 |
| Function | is a critical component of the SMN complex, the master regulator of spliceosomal snRNP (small nuclear ribonucleoprotein) assembly. |
| Subcellular Localization | ** | Nucleus (Cajal bodies), cytoplasm | |
| Molecular Weight | 175 kDa |
| Amino Acids | 1588 aa |
| Ensembl ID | ENSG00000140988 |
| GeneCards | GEMIN5 |
| Human Protein Atlas | GEMIN5 |
| N-terminal region | Contains the SMN interaction domain |
| WD repeat domain | Forms a beta-propeller structure for protein interactions |
| C-terminal region | Mediates snRNA recognition |
| Alternative splicing | Essential for neuronal-specific splicing patterns |
| Synaptic plasticity | Local snRNP assembly at synapses for activity-dependent splicing |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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